Current Treatment Trials – Now open for recruitment





Welcome to the Beating the Blues before Birth (BBB) study.

You have taken a positive step towards improving your mood and managing the demands of pregnancy.

By joining this study you will be offered either cognitive behavioural therapy for depression during pregnancy or an assessment with advice about enhanced standard care.

If you would like to take part, press the join now button to see if this study is suitable for you.


BBB was developed by the Parent-Infant Research Institute.  This program is based on PIRI’s evaluated treatment for Postnatal Depression and includes features from other PIRI programs. Our recent studies show the effectiveness of BBB in reducing depression and anxiety during pregnancy and improving child developmental outcomes.

As part of the study you will receive an assessment with a psychologist, and be randomly allocated to one of the following depression treatments:

  • BBB program (eight free-of-charge sessions of individual cognitive behavioural therapy, including one couple’s session)
  • Enhanced Standard Care (linkage with your healthcare professional who can provide you with support and treatment).

The benefits of this program to you and your child will be evaluated.

At 24 months of age, your child’s development will also be assessed by a trained clinician and you will be provided with a report.


Milgrom, J., Holt, C., Holt, C.J., Ross, J., Ericksen, J., & Gemmill, A. (2015). A Feasibility Study and Pilot Randomised Trial of an Antenatal Depression Treatment with Infant Follow-up. Archives of Women’s Mental Health, 18(5):717-30.
Milgrom,  J., Holt, C.J., Bleker, L.S., Holt, C., Ross, J., Ericksen,  J., Glover, V., O’Donnell, K.J., de Rooij, S. R., & Gemmill , A.W. (2018). Maternal antenatal mood and child development: an exploratory study of treatment effects on child outcomes up to 5 years. Journal of Developmental Origins of Health and Disease.


To download the Beating the Blues before Birth brochure click here