Depression & Anxiety During Pregnancy Study – Now Open For Recruitment


Beating the Blues before Birth

Welcome to the Beating the Blues before Birth (BBB) study for depression in pregnancy.

You have taken a positive step towards improving your mood and managing the demands of pregnancy.

By joining this study you will be offered either cognitive behavioural therapy for depression (delivered via telehealth) during pregnancy or an assessment with advice about enhanced standard care.

Download the Beating the Blues before Birth brochure to see if this depression in pregnancy study is suitable for you.

If you would like to take part, please Join Now.

Note: We are able to continue the study through the COVID-19 outbreak. Women in the treatment group will receive 8 CBT sessions via telehealth by PIRI’s psychologists. The study may be suitable for you if you are experiencing depression and anxiety during this challenging time.

BBB program has been developed by the Parent-Infant Research Institute as a treatment for depression in pregnancy. This program is based on PIRI’s evaluated treatment for Postnatal Depression and includes features from other PIRI programs. Our recent studies show the effectiveness of BBB in reducing depression and anxiety during pregnancy and in improving child developmental outcomes.

As part of this depression in pregnancy study you will receive an assessment with a psychologist, and be randomly allocated to one of the following depression treatments:

  • BBB program (eight free-of-charge sessions of individual cognitive behavioural therapy, including one couple session)
  • Enhanced Standard Care (linkage with your healthcare professional who can provide you with support and treatment).

The benefits of this program to you and your child will be evaluated.

At 24 months of age, your child’s development will also be assessed by a trained clinician and you will be provided with a report.

Milgrom, J., Holt, C., Holt, C.J., Ross, J., Ericksen, J., & Gemmill, A. (2015). A Feasibility Study and Pilot Randomised Trial of an Antenatal Depression Treatment with Infant Follow-up. Archives of Women’s Mental Health, 18(5):717-30.
Milgrom,  J., Holt, C.J., Bleker, L.S., Holt, C., Ross, J., Ericksen,  J., Glover, V., O’Donnell, K.J., de Rooij, S. R., & Gemmill , A.W. (2018). Maternal antenatal mood and child development: an exploratory study of treatment effects on child outcomes up to 5 years. Journal of Developmental Origins of Health and Disease.